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medi1873 hexameric gitrl fusion protein (gitrl fp)  (AstraZeneca ltd)

 
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    Structured Review

    AstraZeneca ltd medi1873 hexameric gitrl fusion protein (gitrl fp)
    Structure of GITR agonists being evaluated in ongoing or completed clinical trials
    Medi1873 Hexameric Gitrl Fusion Protein (Gitrl Fp), supplied by AstraZeneca ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/gitrl-fp/medi1873/pmc10278658-11-16-2
    Average 90 stars, based on 1 article reviews
    medi1873 hexameric gitrl fusion protein (gitrl fp) - by Bioz Stars, 2026-09
    90/100 stars

    Images

    1) Product Images from "Targeting GITR in cancer immunotherapy – there is no perfect knowledge"

    Article Title: Targeting GITR in cancer immunotherapy – there is no perfect knowledge

    Journal: Oncotarget

    doi: 10.18632/oncotarget.28461

    Structure of GITR agonists being evaluated in ongoing or completed clinical trials
    Figure Legend Snippet: Structure of GITR agonists being evaluated in ongoing or completed clinical trials

    Techniques Used: Binding Assay

    Related Articles

    other:

    Article Title: Recombinant Newcastle Disease Virus Immunotherapy Drives Oncolytic Effects and Durable Systemic Antitumor Immunity
    Article Snippet: Antibodies to PD-1 (cloneRMP4–14; BioXCell), PD-L1 (mouse IgG1; AstraZeneca), GITRL-FP (mouse IgG2a; AstraZeneca), and OX40LFP (mouse IgG1; AstraZeneca) were all administered intraperitoneally.

    Article Title: Novel non-terminal tumor sampling procedure using fine needle aspiration supports immuno-oncology biomarker discovery in preclinical mouse models
    Article Snippet: Mice were randomized by body weight and dosed with mouse glucocorticoid-induced TNFR-related protein ligand-fusion protein (GITRL-FP) mIgG2a (AstraZeneca) intraperitoneally at 0.2 mg/kg or 1 mg/kg 6 days after tumor cell implantation.

    Article Title: Recombinant Newcastle Disease Virus Immunotherapy Drives Oncolytic Effects and Durable Systemic Antitumor Immunity
    Article Snippet: Antibodies to PD-1 (clone RMP4–14; Bio X Cell), PD-L1 (mouse IgG1; AstraZeneca), GITRL-FP (mouse IgG2a; AstraZeneca), and OX40L-FP (mouse IgG1; AstraZeneca) were all administered intraperitoneally.



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    Image Search Results


    Structure of GITR agonists being evaluated in ongoing or completed clinical trials

    Journal: Oncotarget

    Article Title: Targeting GITR in cancer immunotherapy – there is no perfect knowledge

    doi: 10.18632/oncotarget.28461

    Figure Lengend Snippet: Structure of GITR agonists being evaluated in ongoing or completed clinical trials

    Article Snippet: MEDI1873 , AstraZeneca , Hexameric GITRL fusion protein (GITRL FP) comprising 2 GITRL ECD trimers and IgG1 Fc linked by isoleucine zipper trimerization domain , Fully human IgG1 , Yes , Hexavalent.

    Techniques: Binding Assay